Q
what is the coating on aspirin
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The coating on aspirin, also known as enteric coating, is a polymer barrier applied on oral medication that prevents its dissolution or disintegration in the gastric environment. This specialized coating is designed to remain intact in the acidic conditions of the stomach (pH ~1.5 to 3.5) and only dissolve when it reaches the more neutral pH conditions of the small intestine (pH ~5.5 to 7.5). The primary reason for using an enteric coating on aspirin is to minimize its direct irritative effect on the stomach lining, thereby reducing the risk of gastrointestinal discomfort or ulcers which can be a side effect of uncoated aspirin. Additionally, this coating helps in controlling the time of release of the aspirin, ensuring a predictable absorption rate which is crucial for its therapeutic efficacy. The use of enteric-coated aspirin is particularly beneficial for long-term users or those with known gastric sensitivities.
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