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Q
which amino acid is classified as basic
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In biochemistry, basic amino acids are those with side chains that contain a nitrogen atom capable of accepting a hydrogen ion, giving it a positive charge at physiological pH. The three amino acids classified as basic are lysine, arginine, and histidine. Lysine and arginine have side chains that are positively charged under all physiological conditions, making them strongly basic. Histidine, however, has a side chain with an imidazole group, which can be positively charged under certain conditions. This gives histidine the unique ability to function at or near the physiological pH (7.35-7.45), acting as a buffer and playing a critical role in enzyme active sites by participating in acid-base catalysis. Understanding the properties of basic amino acids is crucial in biochemistry and molecular biology, particularly in the study of protein structure, function, and enzyme mechanisms.
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