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Q
which amino acid in the substrate binding pocket
I'm a seasoned industrial engineer with a keen interest in machine learning. Here to share insights on latest industry trends.
The question "which amino acid in the substrate binding pocket" requires context, such as specifying the enzyme or protein of interest. Generally, the substrate binding pocket in enzymes contains specific amino acids that interact with substrates. Common amino acids include Serine, Threonine, and Tyrosine for hydrogen bonding; Aspartate and Glutamate for acidic interactions; Lysine and Arginine for basic interactions; and Phenylalanine, Tryptophan, and Leucine for hydrophobic interactions. These interactions stabilize the substrate, facilitating catalysis. Understanding these interactions can guide the design of inhibitors or guide mutations to alter enzyme specificity.
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