Q
why is arginine not an indispensable amino acid
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Arginine is classified as a conditionally essential amino acid, meaning it is generally not indispensable because the body can synthesize it. However, during periods of rapid growth, illness, or stress, endogenous synthesis may not meet the body's demands, making dietary intake necessary. In adults, arginine synthesis is typically sufficient, but in infants or those with certain health conditions, it becomes more essential. The body produces arginine from citrulline, another amino acid, via the urea cycle. Factors like inadequate growth hormone production can also affect arginine synthesis, highlighting its conditional nature depending on physiological states.
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