Q
where does rna polymerse bind
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RNA polymerase binds to a specific region of the DNA called the promoter, which is located at the beginning of a gene. The promoter contains specific sequences that signal the RNA polymerase where to begin transcription of the gene into RNA. These sequences vary among different organisms but serve the same fundamental role of initiating transcription. In bacteria, common promoter sequences include the -10 (TATAAT) and the -35 (TTGACA) regions, named for their approximate location in nucleotides upstream of the transcription start site. In eukaryotes, the promoter complexity increases, involving multiple elements such as the TATA box, initiator elements, and upstream promoter elements that interact with various transcription factors to recruit RNA polymerase II for gene transcription. This precise interaction ensures that genes are expressed at the right time and place within an organism, playing a critical role in gene regulation and cellular function.
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