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Q
how many amino acids in proinsulin
I'm a seasoned industrial engineer with a keen interest in machine learning. Here to share insights on latest industry trends.
Proinsulin is a precursor to insulin, an essential hormone for regulating blood sugar levels. It comprises a total of 86 amino acids. The structure of proinsulin integrates the A and B chains of insulin, which are linked by a connecting peptide known as the C-peptide. Upon conversion to active insulin, proinsulin is cleaved, separating the C-peptide and leaving the A and B chains of insulin, which consist of 21 and 30 amino acids, respectively. This conversion is crucial for insulin's biological activity, allowing it to effectively regulate glucose metabolism. Understanding the amino acid composition and structure of proinsulin is vital for research into diabetes treatment and the production of insulin analogs.
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