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PVC stands for Premature Ventricular Contraction, a common cardiac arrhythmia evident on an ECG (Electrocardiogram). It occurs when an extra heartbeat arises from the ventricles (the heart's lower chambers) before a normal heartbeat. On an ECG, a PVC appears as a premature and unusually shaped QRS complex, often followed by a compensatory pause. While PVCs can be benign, occurring in healthy individuals without heart disease, frequent PVCs or those presenting with certain patterns may indicate underlying heart conditions and necessitate further evaluation by a healthcare professional. Lifestyle modifications and, in some instances, medication or procedures may be recommended based on their frequency and impact.
The primary structure of amino acids in a protein is the sequence in which amino acids are linked together by peptide bonds to form a polypeptide chain. Each protein has a unique sequence of amino acids that determines its structure and function. The amino acid sequence is encoded by the genetic material of an organism and dictates how the polypeptide folds into its three-dimensional shape, crucial for the protein's activity. This sequence is fundamental in the study of biochemistry and molecular biology as alterations in the sequence can lead to significant changes in the protein's properties and its interaction with other molecules, impacting biological processes and potentially leading to diseases.
The assertion that every protein ends with a specific amino acid is a common misconception. In reality, while every protein starts with the amino acid methionine (in eukaryotes) or a modified form like N-formylmethionine (in prokaryotes), due to the universal start codon AUG, the ending amino acid of proteins can vary widely. This variance is due to the diverse set of stop codons (UAA, UAG, UGA) that do not code for any amino acid but signal the end of the amino acid chain during protein synthesis. Therefore, it's not accurate to say that there's a universal terminal amino acid for all proteins. Instead, the final amino acid is determined by the gene coding for the protein and can be any of the 20 standard amino acids involved in protein synthesis, depending on the sequence.
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