Q
why is histine the first amino acid in glucagon
I'm a seasoned industrial engineer with a keen interest in machine learning. Here to share insights on latest industry trends.
Histidine is the first amino acid in glucagon due to its gene coding and post-translational modifications. Glucagon, a hormone crucial for glucose metabolism, is synthesized as preproglucagon in pancreatic alpha cells. Its gene sequence specifically codes for histidine to be at the N-terminal of the hormone's mature form. This positioning is not arbitrary; the presence of histidine at the start of glucagon plays a role in the hormone's stability and function. Histidine's unique imidazole side chain may contribute to the specific folding or interaction patterns of glucagon, affecting its receptor binding and activity. Moreover, the evolutionary conservation of histidine in this position across different species suggests its importance for the hormone's biological activity. While the precise reasons for histidine’s primacy in glucagon's structure may involve complex biochemical interactions and evolutionary pressures, its role underscores the intricate design and regulation of hormonal functions in glucose metabolism.
You May Like
You May Like
Q&A
- •what happens when you burn polyethylene
- •how does soft foam ink brayer work
- •why microcrystalline cellulose does not absorb reactive dye
- •what is epoxy putty used for
- •where to buy alumilite resin
Popular Information
- •How is Europe’s energy crisis impacting Chinese caustic soda markets?
- •Perstorp to increase production of 2-ethylhexanoic acid
- •The Price of Caustic Soda Rose Strongly This Week (September 19-23)
- •China PE Market Saw a slight Increase Last Week (January 1-5)
- •EPA takes first step in potentially banning vinyl chloride