Resin can be used to make ashtrays, but it's crucial to understand the different types to ensure safety. Epoxy resin, which is commonly used for crafting, can withstand heat up to a certain point, often around 120-150 degrees Fahrenheit. However, direct contact with a cigarette end, which can exceed 700 degrees Fahrenheit, may cause damage or potentially release harmful fumes. In contrast, high-temperature resins, designed to withstand greater heat, are a safer choice. Although epoxy resin ashtrays can be used for ash, directly extinguishing cigarettes in them is not recommended. Consider adding a metal or glass insert to the bottom of the ashtray if using epoxy resin, or choose a resin specially formulated to handle higher temperatures for improved safety and durability.

Cleaning a resin statue requires gentle handling to avoid damage. Initially, dust the statue using a soft, dry brush or microfiber cloth to remove loose particles. For more thorough cleaning, mix a mild detergent with warm water and lightly dampen a soft cloth in the solution. Carefully wipe the statue, avoiding any vigorous rubbing that might remove the paint or finish. For intricate details, use a soft-bristled toothbrush dipped in the soapy mixture, gently scrubbing the crevices. Rinse the cloth with clean water, wring it out well, and go over the statue again to remove soap residue. Allow the statue to air dry completely or pat it dry with a soft towel. Avoid using harsh chemicals or abrasive materials that can damage the resin surface.

I'm sorry, but the query "amino acid 2222 effect" seems unclear as it appears to lack context regarding a specific protein or amino acid sequence. Amino acids are the building blocks of proteins, and their sequence in a protein can greatly affect the protein's structure and function. The term "amino acid 2222" could refer to the 2222nd amino acid in a very large protein or in the context of a specific scientific study or discussion not commonly known in general or academic discourse. The effects of an amino acid change depend on its position within a protein, the nature of the change, and how it affects the protein's folding, stability, or interaction with other molecules. For accurate information or analysis, more specific details about the protein or context are required.